DOT Compliance and Cannabis Regulations in Trucking: What Carriers and Drivers Must Know

March 31 2025

Matrix Inc. | Experts in Safety-First Transportation for Over a Decade

The intersection of DOT compliance and cannabis regulations in trucking is becoming more complex with every passing year. As more states legalize marijuana and CBD products gain popularity, trucking companies and drivers are left navigating a confusing legal landscape. At Matrix Inc., our 11+ years of experience have taught us that staying ahead of these shifts is not just about following the rules—it’s about protecting careers, reducing risk, and keeping roads safe.

Here’s what every fleet, driver, and logistics partner needs to know about cannabis use, DOT regulations, and what comes next for our industry.

As of 2025:

  • 23 states allow recreational marijuana use
  • 39 states permit medical marijuana use

Yet, marijuana remains federally illegal, and the Department of Transportation (DOT) enforces a strict zero-tolerance policy—no exceptions, even if drivers use cannabis legally under state law.

This disconnect creates serious risks for drivers, who could lose their jobs over a legally purchased product, and for carriers, who face major compliance issues if a driver fails a drug test.

At Matrix Inc., we stay ahead of these risks with clear protocols and driver education—helping our team avoid career-ending mistakes while keeping our fleet in full compliance.

2. CBD Products: A Hidden Risk

CBD is often seen as a safe alternative to THC for pain and anxiety relief. But here’s the problem: many CBD products contain trace amounts of THC—even if they’re labeled “THC-free.” Those traces can accumulate in the body, triggering a positive DOT drug test.

This puts even responsible, well-intentioned drivers at risk. That’s why Matrix takes a proactive stance—educating drivers about product risks and maintaining a no-compromise stance on safety.

3. Driver Retention Takes a Hit

The trucking industry faced a shortage of 80,000+ drivers in 2024, according to the ATA—and the number is climbing. Add cannabis confusion to the mix, and retention becomes even harder.

Drivers are often disqualified after failing a test they didn’t realize would be an issue. Some carriers offer a second chance; others don’t. Either way, recovery is costly—both for the driver and for the carrier forced to fill the gap.

At Matrix, we work to prevent disqualifications before they happen—equipping our drivers with real knowledge, realistic expectations, and expert support.

4. Where Do Drivers and Carriers Go from Here?

The path forward depends on how we educate, innovate, and advocate. Here’s what the industry must focus on:

Driver Education: Safety Starts with Understanding

Many drivers don’t realize that marijuana stays in the body far longer than alcohol.

👉 Unlike alcohol intoxication, which typically wears off within 8 hours, marijuana impairment can last up to 36 hours after a single use.
👉 Some research shows cognitive and motor effects may linger for up to a week.

That’s a serious safety concern for commercial drivers handling 80,000-pound vehicles on public roads.

At Matrix Inc., we regularly update our team on these facts—not just to meet compliance, but to keep people safe.

Improved Testing Methods

Today’s DOT tests detect THC long after a driver is no longer impaired. This leads to false positives and lost jobs for drivers who are safe to operate but still show “positive” due to residual traces.

Oral fluid testing has been approved by the DOT (pending lab certification) and could revolutionize how we assess current impairment vs. past usage. It’s a fairer, more accurate approach—and Matrix supports innovations that promote both safety and justice.

Clearer CBD Regulation

Many THC-positive results are due to mislabeled CBD products. We support stricter labeling laws and call for regulatory oversight to ensure products marked “THC-free” actually are.

In the meantime, Matrix recommends drivers avoid CBD entirely to protect their careers—until we can trust product safety and regulation.

Policy Advocacy

It’s time for the industry to speak with one voice. From safety advocates to state trucking associations, we must push for modernized federal policies that align with evolving state laws and medical realities—without compromising road safety.

Matrix supports efforts to bridge this legal gap while prioritizing safe, well-informed, and empowered drivers.

5. Matrix Inc.’s Commitment: Beyond Compliance

With 11+ years in business and a team boasting over 150 years of combined dispatch experience, Matrix Inc. is more than just a carrier—we’re a safety-first, driver-focused powerhouse.

We invest in:

  • Ongoing driver training
  • Real-time compliance systems
  • Transparent communication
  • Support for every step of your career

Our results speak for themselves: zero compromises on safety, full alignment with federal regulations, and a track record that drivers and clients trust.

Ready to drive with a company that puts safety and your career first?
Explore opportunities at Matrix Inc.—where compliance meets compassion, and experience drives everything.